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Shock! 3d printing high-precision brain model only takes an hour

DateTime: 2018-06-01
浏览次数: 120

Researchers at Harvard and MIT have proposed a simple method for 3D printing of highly detailed human brain models in less than an hour - the cost of only a small fraction of low-quality products and Manpower.


In theory, medical imaging technologies such as MRI and CT scan can produce high-resolution images and use them as a series of “slices”, which just fits the working principle of 3D printers. These printers also use Slice print. However, Steven Keating, an MIT graduate, found that when he wanted to examine his brain after surgical removal of a baseball-sized tumor, the current method was too cumbersome and time-consuming, and failed to accurately reveal important features.

Steven Keating collaborated with a team of scientists, including Dr. James Weaver, a senior research scientist at the Wyss Institute, and Dr. Neri Oxman, the director of the Mediated Matter team at the MIT Media Lab and an associate professor at the School of Media Arts and Sciences. Dr. Neri Oxman is dedicated to developing a new technology that enables MRI and CT scan images to be quickly and easily converted to physical models with unprecedented detail.

The new method provides a fast and highly accurate method for converting complex images into a format that can be easily 3D printed. The key is to use a dithered bitmap for printing, which is a digital file format in which each pixel of a grayscale image is converted to a series of black and white pixels, while the density of black pixels defines different shades of gray instead of pixels. The color itself changes.


Different sizes of black ink dots are used to convey images with black-and-white newspapers to convey similar shades, and the more black pixels present in a given area, the more black. By mitigating all pixels from various gray shades into a mix of black and white pixels, the dithered bitmap allows the 3D printer to print complex medical images using two different materials, retaining the original data with greater precision and speed All minor changes.

The researchers used bitmap-based 3D printing to create Keating's brain and tumor models, which faithfully preserved all the levels of detail that existed in the raw MRI data, up to the same resolution as the human eye can distinguish—9-10 inches. Far observation distance. Using this same method, they were also able to use the different materials of the valve tissue and the formed mineral plaque in the valve to print a variable stiffness model of the human heart valve, resulting in a model that exhibits a mechanical performance gradient and new A deeper understanding of the actual effect of plaques on valve function.


Ahmed Hosny holds a Steven Keating tumor model, Steven Keating holds his skull model, and James Weaver holds Keating's MRI scan model.

Weaver said: "Our approach not only retains a high level of detail and prints it into a medical model, but it also saves a lot of time and money. For example, manually segmenting a CT scan of a healthy person's foot, for example, all its internals Skeletal structures, bone marrow, tendons, muscles, soft tissues and skin all take more than 30 hours, even by highly trained professionals, and we can do it in less than an hour."


Researchers hope that their method can help 3D printing become a more feasible tool for routine examination and diagnosis, medical education, and understanding of the human body. “Now, for the hospital, hiring a team of experts to manually divide the 3D printed image data sets, unless it is an extremely high risk or high risk case, this is too expensive for the hospital, and we hope to change this situation.” Wyss Institute researcher Ahmed Hosny said.

"I think at some point in the next five years, any patient who enters a doctor's office for routine or non-conventional CT or MRI scans can get their specific patient's 3D print model data in a matter of days," Weaver said.

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